研究进展

J Biomed Res: Cumulative live birth rates of in vitro fertilization/intracytoplasmic sperm injection after multiple complete cycles in China

2020-08-14

Abstract

 There were few studies of cumulative live birth rates (CLBRs) based onmulticenter reproductive clinical data from the general Chinese population.Here we report a retrospective cohort study, including 14 311 women with 17 315cycles, in three reproductive centers to evaluate two estimated parameters ofCLBRs with multiple transfer cycles of in vitro fertilization(IVF)/intracytoplasmic sperm injection (ICSI) in a Chinese population. We found
 that CLBRs were related to female age and endometrial thickness. By the fourthtransfer cycle, the conservative and optimal estimates of CLBRs were 52.95% and77.30% in women under 30 years of age, and 18.17% and 26.51% in those 37 yearsof age or older, respectively. The two estimates were 44.70% and 63.15% inwomen with endometrial thickness more than 7 mm, and 32.05% and 46.18% in thosewith less than 7 mm, respectively. In addition, body mass index (BMI), durationof infertility, and infertility diagnoses may also be related to CLBRs oncertain conditions. The findings from this study on CLBRs after multipletransfer cycles of IVF/ICSI treatment on different conditions in the Chinesepopulation should be beneficial to both infertile couples and clinicians.


引用本文:

Huang L, Lu Q, Du J, Lv H, Tao S, Chen S, Li X, Han X, Zhou K, Xu B, Liu X, Ma H, Xia Y, Jin G, Shen H, Ling X, Hu Z, Tan J, Diao F. Cumulative live birth rates of in vitro fertilization/intracytoplasmic sperm injection after multiple complete cycles in China. J Biomed Res. 2020 Aug 14;34(5):361-368. doi: 10.7555/JBR.34.20200035. PMID: 32981896; PMCID: PMC7540236.

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